Thermo Fisher Scientific CD69 Monoclonal Antibody (FN50), APC, eBioscience

Applications and Tested Dilution

• Application: Flow Cytometry (Flow)
• Tested Dilution: 5 µL (0.015 µg)/test
• Publications: View 29 publications

Product Specifications

Available Formats

• Unconjugated
• Alexa Fluor 561
• Alexa Fluor 660
• APC-eFluor 780
• Biotin
• Brilliant UV 395 / 615 / 661 / 737 / 805
• Brilliant Violet 421 / 480 / 650 / 711 / 786
• eFluor 450
• FITC
• NovaFluor Blue 610-70S
• PE / PE-Cyanine7 / PE-eFluor 610
• PerCP-eFluor 710
• Super Bright 436 / 600 / 780
• Request custom conjugation

Product Specific Information

The FN50 monoclonal antibody reacts with human CD69 (very early activation antigen, VEA), a ~30 kDa disulfide-linked dimer expressed on lymphocytes, monocytes, and platelets. CD69 is rapidly upregulated upon activation.

• Applications Reported: Flow cytometric analysis
• Applications Tested: Pre-titrated and validated for 5 µL (0.015 µg) per test in 100 µL final volume.
• Excitation: 633–647 nm
• Emission: 660 nm
• Laser: Red Laser
• Filtration: 0.2 µm post-manufacturing filtered

Target Information

CD69 (AIM, Active Inducer Molecule) is a gp28/34 disulfide-bonded homodimer (~60 kDa under non-reducing conditions). It contains one or two N-linked oligosaccharides and is expressed on activated platelets. CD69 is involved in lymphocyte signal transduction and is induced upon T lymphocyte activation, potentially playing a role in proliferation. It may also transmit signals in natural killer cells and platelets.
Diseases associated with CD69 dysfunction include coccidiodomycosis and asthma.
Alternative splicing results in multiple transcript variants of CD69.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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