Thermo Fisher Scientific Cullin 3 Recombinant Rabbit Monoclonal Antibody (ARC0102)
Rabbit 모노클로날 항체로 인간, 마우스, 랫트의 Cullin 3 단백질 검출에 사용. WB, IHC(P), ELISA에 적합. 고순도 Affinity Chromatography 정제. 안정한 액상 형태로 -20°C 보관 권장. 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC0102 |
| Immunogen | A synthetic peptide corresponding to amino acids 669–768 of human Cullin 3 (Q13618) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.35 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849227 |
Product Specific Information
Immunogen sequence:
LHRVKIQTVA AKQGESDPER KETRQKVDDD RKHEIEAAIV RIMKSRKKMQ HNVLVAEVTQ QLKARFLPSP VVIKKRIEGL IEREYLARTP EDRKVYTYVA
Target Information
Cullin 3 is a member of the human cullin gene family (CUL1, 2, 3, 4a, 4b, and 5), homologous to the S. cerevisiae cdc53 gene. CUL1 forms a complex with human p19 skp1 and F-box protein p45 skp2, creating a ubiquitin ligase complex that regulates proteolysis of G1 cell cycle proteins. Unlike CUL1, CUL2 forms a complex with the transcriptional elongation complex SIII (Elongin C, Elongin B, and VHL), though the function of this association remains unknown.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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