Thermo Fisher Scientific CD9 Polyclonal Antibody
CD9 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, Flow Cytometry에 적합합니다. 인간 CD9에 반응하며, 고순도 액상 형태로 제공됩니다. 세포 부착, 이동, 신호전달 연구에 활용됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Flow Cytometry (Flow) | 1:10–1:50 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 21–51 amino acids of human CD9 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.7 mg/mL |
| Purification | Size-exclusion, Dialysis, Ammonium sulfate precipitation |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2075890 |
Target Information
CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophils, stimulated T lymphocytes, and by neurons and glial cells in the peripheral nervous system.
CD9 belongs to the tetraspanin family, which spans the membrane four times. In pre-B cells and platelets, CD9 regulates cell activation and aggregation through association with integrin CD41/CD61 (GPIIb/GPIIIa).
It is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion. CD9 plays roles in cell attachment, proliferation, and is necessary for association of heterologous MHC II molecules on dendritic cells for effective T cell stimulation.
CD9 expression is critical for suppression of cancer cell motility and metastasis and is considered a metastasis suppressor in solid tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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