Thermo Fisher Scientific SMC1 Recombinant Rabbit Monoclonal Antibody (SN20-27)
SMC1 단백질을 인식하는 재조합 토끼 모노클로날 항체로, Western blot, IHC, ICC 등 다양한 응용 가능. 높은 특이성과 민감도, 로트 간 일관성, 동물 유래 성분 없음. 단기 4°C, 장기 -20°C 보관.
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Thermo Fisher Scientific SMC1 Recombinant Rabbit Monoclonal Antibody (SN20-27)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SN20-27 |
| Immunogen | Synthetic peptide within Human SMC1A aa 1,184–1,233 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809622 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and screened to select optimal candidates.
Advantages include:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
Structural Maintenance of Chromosomes (SMC) family proteins are essential for nuclear events involving chromosome structural changes, such as mitotic organization, DNA recombination and repair, and transcriptional repression.
SMC1 and SMC3 form a heterodimeric complex required for metaphase progression and sister chromatid cohesion. Mutations in the SMC1 gene can cause Cornelia de Lange syndrome 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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