Thermo Fisher Scientific CD13 Monoclonal Antibody (OTI2F10), TrueMAB
인간 CD13(ANPEP)을 표적으로 하는 마우스 단클론 항체로, Western blot 및 IHC에 사용 가능. 비결합형 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도. 염화칼륨 완충액 기반, 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2F10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 668–967 of human ANPEP produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
CD13 (ANPEP) is a 150–170 kDa type II transmembrane zinc-binding ectopeptidase expressed on various cell types.
It catalyzes removal of neutral amino acids from small peptides, modulating bioactive peptide activity.
CD13 participates in extracellular matrix degradation, antigen processing, and signal transduction, and plays roles in inflammation, cell motility, and vascularization.
It is expressed by granulocytes, monocytes, and myeloid leukemia cells, contributing to leukemic cell survival and correlating with poor carcinoma prognosis.
CD13 also functions as an aminopeptidase enzyme and serves as an alpha receptor for coronavirus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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