Thermo Fisher Scientific CD127 Polyclonal Antibody
Thermo Fisher Scientific의 CD127 Polyclonal Antibody는 Mouse 시료에 반응하며 Western blot에 적합합니다. Goat에서 유래한 Polyclonal IgG로, IL-7 수용체 연구에 사용됩니다. 0.5 mg/mL 농도의 액상 형태로 제공되며, -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–2 µg/mL
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence DDHSFWCHSQLE |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933407 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000.
Target Information
CD127 (Interleukin-7 receptor, IL-7R) is a glycoprotein involved in the regulation of lymphopoiesis. The response of cells to CD127 depends on the presence of IL7R, an alpha/gamma chain heterodimer.
The gamma(c) chain associates with the interleukin-2 receptor and activates signal transduction, while the alpha chain determines specific signaling via cytoplasmic molecules.
CD127 promotes proliferation of precursor B cells, thymocytes, T cell progenitors, and mature CD4+ and CD8+ T cells.
Dysfunction of CD127 is associated with severe combined immunodeficiency disorders.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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