Thermo Fisher Scientific KEAP1 Polyclonal Antibody
Human KEAP1 단백질을 인식하는 Goat Polyclonal 항체로, IHC(P) 및 ICC/IF에 적합합니다. 비결합(Unconjugated) 형태이며, 0.5 mg/mL 농도의 액상 시약입니다. TBS buffer(pH 7.3, 0.5% BSA)로 보관되며, -20°C에서 냉동 보관이 권장됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 3–5 µg/mL |
| Immunocytochemistry (ICC/IF) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-EVTPSQHGNRTFS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933406 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000.
Target Information
The KEAP1 gene encodes a protein containing KELCH-1-like domains and a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 (Nrf2) in a redox-sensitive manner. Upon dissociation in the cytoplasm, Nrf2 translocates to the nucleus, inducing expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been identified.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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