Thermo Fisher Scientific CD4 Monoclonal Antibody (74-12-4), APC
돼지 CD4 항원을 인식하는 단클론 항체로, APC 형광체가 결합되어 유세포분석(Flow Cytometry)에 적합합니다. 고순도 정제 항체이며 4°C에서 보관하며 동결 금지. 다양한 형광체 포맷으로 제공됩니다.
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Applications
- Flow Cytometry (Flow)
Tested Dilution: 0.2 µg/10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Pig |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 74-12-4 |
| Immunogen | Fresh dd miniature swine thymocytes |
| Conjugate | APC (Allophycocyanin) |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.5, with proprietary stabilizer |
| Contains | <0.1% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE! |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745689 |
Additional Formats
- Unconjugated (MA5-28735)
- Biotin (MA5-28731)
- FITC (MA5-28732)
- PE (MA5-28733)
- PE-Cyanine5 (MA5-28734)
- Request custom conjugation available
Target Information
The CD4 antigen is involved in the recognition of MHC class II molecules and acts as a co-receptor for HIV. CD4 is primarily expressed in T helper cells, but can also be found in monocytes, macrophages, and dendritic cells. At the tissue level, CD4 expression is observed in thymus, lymph nodes, tonsils, spleen, and certain regions of the brain and gut. It plays a role in T-cell activation through association with the T-cell receptor complex and protein tyrosine kinase Lck, and may contribute to neuronal damage in infectious and immune-mediated CNS diseases. Multiple alternatively spliced transcripts have been identified (RefSeq, July 2017).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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