Thermo Fisher Scientific EphB1 Polyclonal Antibody
인간 EphB1 단백질을 인식하는 Sheep 유래 Polyclonal 항체로, IP 등 다양한 연구용 응용에 적합합니다. 액상 형태로 제공되며 1 mg/mL 농도, PBS 버퍼 및 sodium azide 포함. 신경계 발달 및 혈관 형성 연구에 활용 가능.
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Applications
Immunoprecipitation (IP)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to residues 586–984 of C terminus of human EphB1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | PBS |
| Contains | 0.08% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1074248 |
Product Specific Information
A suggested positive control for this product is human brain lysate.
Target Information
EPHB1 is a receptor tyrosine kinase belonging to the ephrin receptor family. Members of the Eph family play important roles in biological processes such as nervous system development, angiogenesis, and neural synapse formation and maturation.
EphB1 and other EphB family members are type I membrane-spanning proteins composed of immunoglobulin, fibronectin type III, and cysteine-rich subdomains in the ectodomain, with a cytoplasmic tyrosine kinase domain upstream of a carboxyterminal SAM domain.
EphB family proteins bind ephrin-B class ligands, which are also transmembrane proteins capable of bidirectional signaling. EphB1 is mainly expressed in developing neural structures and vascular epithelium. Upon binding ephrin B1, EphB1 regulates cell attachment and assembly. These proteins are implicated in neuronal and vascular cell targeting.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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