Thermo Fisher Scientific Acid Phosphatase 1 Polyclonal Antibody
Acid Phosphatase 1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot 및 Immunoprecipitation에 적합합니다. 다양한 종(Bovine, Human, Mouse, Rat)에 반응하며, 고순도 액상 형태로 연구용으로 제공됩니다.
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Thermo Fisher Scientific Acid Phosphatase 1 Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): Assay-dependent
- Immunoprecipitation (IP): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Human, Mouse, Rat |
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant human Protein Tyrosine Phosphatase expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | PBS |
| Contains | 0.08% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2221812 |
Target Information
Low molecular weight protein tyrosine phosphatases, including the human red cell phosphatase HCPTP, are widely expressed cytosolic proteins of approximately 18 kDa that exist in distinct isoforms and are highly selective for phosphotyrosine over phosphoserine or phosphotyrosine.
The HCPTP-A and HCPTP-B proteins expressed in human red cells and placenta are fast and slow forms of red cell acid phosphatase. Like other tyrosine phosphatases, HCPTP is sensitive to inhibition by vanadate and has a catalytic mechanism involving formation of a cystinylphosphate intermediate.
The crystal structure of the bovine heart-derived enzyme BHPTP shows a four-stranded central parallel β-sheet with flanking α-helices and an active site cysteine residue in the typical tyrosine phosphatase sequence context, CXXXXXR.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송 정보
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