Thermo Fisher Scientific MIDN Polyclonal Antibody
MIDN 단백질을 검출하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 적합하며 인간 및 생쥐 시료 반응. 고순도 항원 친화 크로마토그래피 정제, 액상 형태로 제공. 연구용으로만 사용 가능.
- 카탈로그번호
- PA550521
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues near the N-terminal of human Midnolin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635974 |
Product Specific Information
The antibody detects endogenous levels of total MIDN protein.
Target Information
Expression of the midnolin gene is developmentally regulated: it is strongly expressed in the mesencephalon (midbrain) of the embryo at day 12.5 (E12.5) in mice. The midnolin gene encodes a protein of 508 amino acids containing a ubiquitin-like domain. Intracellular localization studies using midnolin-GFP fusion proteins show that midnolin is localized in the nucleus and nucleolus, but not in the cytoplasm. The nucleolar localization signal is a 28 amino acid peptide located at the C-terminal region of midnolin. It may be involved in the regulation of genes related to neurogenesis in the nucleolus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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