Thermo Fisher Scientific BAZ2A Polyclonal Antibody
Thermo Fisher Scientific의 BAZ2A Polyclonal Antibody는 인간, 마우스, 랫트 시료에 반응하며 WB, IHC, ICC, ELISA 등에 사용 가능. Rabbit IgG 폴리클로날 항체로 고순도 정제 및 안정적 액상 형태 제공. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 97–295 of human BAZ2A (NP_038477.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.03 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914137 |
Product Specific Information
- Positive test controls include: K-562, NIH/3T3
- Immunogen sequence:
QYPSANPGSN LKDPPLLSQF SGGQYPLNGI LGGSRQPSSP SHNTNLRAGS QEFWANGTQS PMGLNFDSQE LYDSFPDQNF EVMPNGPPSF FTSPQTSPML GSSIQTFAPS QEVGSGIHPD EAAEKEMTSV VAENGTGLVG SLELEEEQPE LKMCGYNGSV PSVESLHQEV SVLVPDPTVS CLDDPSHLPD QLEDTPILS
Target Information
TIP5 is the large subunit of the nucleolar remodeling complex NoRC, which represses ribosomal gene transcription. Histone deacetylation is involved in this repression, and TIP5 associates with HDAC1 to mediate histone deacetylation near the rDNA promoter. The interaction between TIP5 and HDAC1, necessary for transcriptional repression, is established by the C-terminal PHD finger and bromodomain.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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