Thermo Fisher Scientific Cdc23 Polyclonal Antibody
Rabbit polyclonal antibody against human CDC23, validated for Western blot. Recognizes amino acids 267–311. High purity (>95%) and antigen affinity purified. Supplied in PBS with 50% glycerol, suitable for research use only.
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 267–311 of Human CDC23 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803672 |
Product Specific Information
- Purity is >95% by SDS-PAGE.
Target Information
Ubiquitination is a key mechanism for targeting short-lived or abnormal proteins for degradation through coordinated action of three enzyme classes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin-protein ligases (E3s).
Ubr2 (Ubiquitin-protein ligase E3-alpha-2), also known as N-recognin-2, is a 1755 amino acid protein containing one UBR-type and one RING-type zinc finger. It functions as an E3 ubiquitin-protein ligase within the N-end rule pathway, recognizing and binding proteins with destabilizing N-terminal residues to promote ubiquitination and degradation. Mice lacking Ubr2 are infertile due to defects in male meiosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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