Thermo Fisher Scientific Phospho-CXCR2 (Ser347) Polyclonal Antibody
Phospho-CXCR2 (Ser347) 항체로, 인산화된 CXCR2 단백질의 Ser347 부위를 특이적으로 인식합니다. Western blot, IHC, ICC/IF에 사용 가능하며, 다양한 종(인간, 마우스, 비인간 영장류)에 반응합니다. Rabbit polyclonal IgG 형태로, 1 mg/mL 농도의 액상 시약입니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate |
| Published species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CXCR2 (Accession P25025), corresponding to amino acid residues around phosphorylated Ser347. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2816323 |
Product Specific Information
This antibody detects endogenous levels of CXCR2 only when phosphorylated at Serine 347.
Target Information
CXCR2 is a receptor for interleukin-8 (IL-8), a potent neutrophil chemotactic factor and a member of the GPCR family. Binding of IL-8 to CXCR2 activates neutrophils through a G-protein–mediated phosphatidylinositol-calcium second messenger system.
CXCR2 binds IL-8, GRO/MGSA, and NAP-2 with high affinity and is expressed in various tissues. ESTs have been isolated from human placenta and thymus libraries.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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