Thermo Fisher Scientific COX8A Polyclonal Antibody
COX8A 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 실험에 적합합니다. 인간, 생쥐, 랫트에서 반응하며 고순도 Affinity chromatography로 정제되었습니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA599809
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human COX8A (Accession P10176), corresponding to amino acid residues M1–F51 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2818742 |
Product Specific Information
Antibody detects endogenous levels of total COX8A.
Target Information
The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water and ATP.
The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some of which are nuclear.
The COX8 (cytochrome c oxidase subunit VIII) subunits are nuclear and have muscle and non-muscle-specific isoforms.
COX8 exists as three isoforms:
- COX8a: liver and heart isoform
- COX8b: heart-specific isoform
- COX8c: expression pattern not yet elucidated
All three COX8 isoforms exist as components of the COX complex and play an important role in electron transport.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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