Thermo Fisher Scientific Phospho-MCM2 (Ser41) Polyclonal Antibody
Phospho-MCM2 (Ser41) 폴리클로날 항체로 인간 및 생쥐에 반응하며, Western blot과 IHC에 적합합니다. 항원 친화 크로마토그래피로 정제된 고품질 항체로 DNA 복제 조절 연구에 활용됩니다. 4°C 보관, 1년 유효기간.
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Thermo Fisher Scientific Phospho-MCM2 (Ser41) Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:5,000–1:20,000 |
| Immunohistochemistry (IHC) | 1:1,000–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:5,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphorylated peptide representing a portion of human Minichromosomal Maintenance Deficient 2 surrounding Serine 41 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with X. laevis and X. tropicalis
Target Information
MCM2 (Mini chromosome maintenance protein 2) is involved in regulating DNA replication. Also known as CDCL1, mitotin, and BM28, MCM2 is a human nuclear protein crucial in the cell cycle, particularly in the onset of DNA replication and cell division. It is similar to early S-phase proteins and has been mapped to 3q21. CDCL1 is considered a candidate oncogene affected by chromosomal breaks in acute myeloid leukemia (AML).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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