Thermo Fisher Scientific GPR125 Polyclonal Antibody
GPR125 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal antibody. Western blot 및 ICC/IF에 사용 가능하며, 인간 시료에 반응. Affinity chromatography로 정제된 액상 형태로, -20°C에서 보관. 연구용 전용.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 | View 1 publication |
| Immunocytochemistry (ICC/IF) | – | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ADGRA3 (Accession Q8IWK6), corresponding to amino acid residues S1079–S1129. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818824 |
Product Specific Information
This antibody detects endogenous levels of total GPR125.
Target Information
G protein-coupled receptors (GPRs), also known as seven transmembrane receptors or 7TM receptors, form a superfamily of proteins involved in numerous stimulus-response pathways. They mediate extracellular-to-intracellular signal transduction via G protein activation and respond to hormones and neurotransmitters.
GPR125 (G protein-coupled receptor 125), also known as PGR21 or TEM5L, is a 1,321-amino-acid multi-pass membrane protein belonging to the G-protein coupled receptor 2 family and LN-TM7 subfamily. It is a novel orphan adhesion-type G-protein-coupled receptor with five leucine-rich repeats (LRR), an immunoglobulin (Ig) domain, and a GPS domain. GPR125 may function in choroidal and hippocampal responses to brain injury and is suggested as a marker for spermatogonial stem cells. Four isoforms of GPR125 exist due to alternative splicing events.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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