Thermo Fisher Scientific SQSTM1 Recombinant Rabbit Monoclonal Antibody (PS00-61)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:5,000-1:10,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:2,000

-

Immunocytochemistry (ICC/IF)

1:100-1:1,000

-

Flow Cytometry (Flow)

1:1,000

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

PS00-61

Immunogen

Synthetic peptide within Human SQSTM1/ p62 aa 400 to the C-terminus if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SQSTM1,uniProtId:Q13501-1,ncbiNodeId:9606,antigenRange:400-440,antigenLength:440,antigenImageFileName:MA5-50706_SQSTM1_Q13501-1_Rabbit.svg,antigenImageFileNamePDP:MA5-50706_SQSTM1_Q13501-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4, with 0.1% BSA, 40% glycerol

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_3094157

Product Specific Information

Positive control: PC-12 cell lysate, RAW264.7 cell lysate, PANC-1 cell lysate, mouse liver tissue lysate, rat brain tissue lysate, SH-SY5Y cell lysate, HeLa cell lysate, Hela-si-NT cell lysate, Hela-si-p62#1 cell lysate, Hela-si-p62#2 cell lysate, human colon carcinoma tissue, A549.

Predicted band size: 48 kDa

Subcellular Location: Cytoplasm, Endoplasmic reticulum, Endosome, Lysosome, Nucleus.

Target Information

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.