Thermo Fisher Scientific UBP1 Monoclonal Antibody (OTI1G8), TrueMAB
UBP1 단백질을 인식하는 마우스 단일클론 항체로 Western blot에 적합. 인간, 마우스, 랫트 반응성. 무보존제, 동결건조 형태로 제공되며 1 mg/mL 농도. 연구용으로 전사 활성 조절 관련 연구에 활용 가능.
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Thermo Fisher Scientific UBP1 Monoclonal Antibody (OTI1G8), TrueMAB
Applications
- Western Blot (WB)
Tested Dilution: 1:500
Species Reactivity
- Human
- Mouse
- Rat
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1G8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 47–269 of human UBP1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
UBP1 acts as a transcriptional activator in a promoter context-dependent manner and modulates placental expression of CYP11A1.
It regulates alpha-globin gene expression in erythroid cells via synergistic interaction with TFCP2.
UBP1 binds strongly to sequences around the HIV-1 initiation site and weakly to the TATA-box, repressing HIV-1 transcription by inhibiting TFIID binding.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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