Thermo Fisher Scientific ELL Monoclonal Antibody (OTI5E12), TrueMAB
ELL 단백질을 인식하는 Mouse Monoclonal Antibody로, WB와 IHC(P) 실험에 적합. Human 시료 반응성. 동결건조 형태로 제공되며, 재구성 시 1 mg/mL 농도로 사용 가능. 연구용으로 RNA polymerase II 전사 조절 연구에 활용.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific ELL Monoclonal Antibody (OTI5E12), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5E12 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 302–621 of human ELL produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
ELL is an elongation factor component of the super elongation complex (SEC), which enhances the catalytic rate of RNA polymerase II transcription by suppressing transient pausing at multiple DNA sites.
It is also part of the little elongation complex (LEC), regulating small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III.
ELL stabilizes RNA polymerase II recruitment/initiation and entry into the pause site, playing an early role before SEC assembly and stabilizing the pre-initiation and early elongation complexes.
[Source: UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.