Thermo Fisher Scientific ELL Monoclonal Antibody (OTI5E12), TrueMAB

Applications and Tested Dilution

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

ELL is an elongation factor component of the super elongation complex (SEC), which enhances the catalytic rate of RNA polymerase II transcription by suppressing transient pausing at multiple DNA sites.
It is also part of the little elongation complex (LEC), regulating small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III.
ELL stabilizes RNA polymerase II recruitment/initiation and entry into the pause site, playing an early role before SEC assembly and stabilizing the pre-initiation and early elongation complexes.
[Source: UniProt]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.