Thermo Fisher Scientific AK1 Monoclonal Antibody (OTI4A1), TrueMAB
AK1 단백질을 인식하는 마우스 모노클로날 항체로, Western blot, ICC/IF, Flow Cytometry에 적합합니다. 인간 유래 단백질을 항원으로 제작되었으며, 고순도의 액상 형태로 제공됩니다. 연구용으로 세포 내 아데닐레이트 키나아제 1 검출에 활용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4A1 |
| Immunogen | Full length human recombinant protein of human AK1 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.89 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates: AK1, AK2, and AK3.
- AK1: Found in the cytosol of skeletal muscle, brain, and erythrocytes
- AK2 and AK3: Found in mitochondria of other tissues including liver and heart
AK1 is associated with a rare genetic disorder causing nonspherocytic hemolytic anemia, where a mutation in the AK1 gene reduces the catalytic activity of the enzyme.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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