Thermo Fisher Scientific Phospho-Nkx2.1 (Ser23) Polyclonal Antibody
Phospho-Nkx2.1 (Ser23) 폴리클로날 항체로 인간, 마우스, 랫트 반응성. Western blot, IHC, ICC/IF에 사용 가능. 인산화된 Ser23 부위에서 TTF1 단백질을 특이적으로 검출. 고순도 정제된 액상 형태로 연구용에 적합.
- 카탈로그번호
- PA5105322
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NKX2-1 (Accession P43699), corresponding to amino acid residues around phosphorylated Ser23 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816750 |
Product Specific Information
This antibody detects endogenous levels of TTF1 only when phosphorylated at Ser23.
Target Information
This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes. It also regulates genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be linked to thyroid cancer. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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