Thermo Fisher Scientific PD-L1 Recombinant Rabbit Monoclonal Antibody (BLR226K)
Thermo Fisher Scientific의 PD-L1 재조합 토끼 단클론 항체(BLR226K)는 Mouse PD-L1 단백질의 세포외 도메인을 인식합니다. Western blot에 최적화되어 있으며, 고순도 액상 형태로 제공됩니다. 연구용으로 PD-1/PD-L1 면역조절 기전 분석에 적합합니다.
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Applications
- Western Blot (WB): Tested dilution 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | BLR226K |
| Immunogen | Recombinant protein representing the extracellular domain of mouse programmed cell death 1 ligand 1 (residues 19–239) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Purified |
| Storage Buffer | BBS, pH 8.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a member of the B7 family. PD-L1 binds to its receptor PD-1, which negatively regulates T-cell receptor (TCR) signaling. Upon receptor binding, PD-L1 decreases TCR-mediated proliferation and cytokine production. PD-L1 is abundantly expressed on many murine and human cancers and can be up-regulated by IFN-gamma stimulation, suggesting its role in tumor immune evasion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
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