Thermo Fisher Scientific PD-L1 Recombinant Rabbit Monoclonal Antibody (BLR227K)
PD-L1 단백질을 표적으로 하는 재조합 토끼 단클론 항체로, Western blot, Flow cytometry, Immunoprecipitation에 사용 가능. 인간 PD-L1의 세포외 도메인을 면역원으로 제작. 고순도 정제 및 1 mg/mL 농도로 제공되며, 4°C에서 보관.
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Applications
- Western Blot (WB): Assay-dependent
- Flow Cytometry (Flow): Assay-dependent
- Immunoprecipitation (IP): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | BLR227K |
| Immunogen | Recombinant protein representing the extracellular domain of Human Programmed cell death 1 ligand 1 (residues 19–238) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Purified |
| Storage Buffer | BBS, pH 8.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a member of the B7 family. It binds specifically to the programmed death receptor 1 (PD-1), which negatively regulates T-cell receptor (TCR) signaling. PD-L1 engagement with PD-1 leads to decreased TCR-mediated proliferation and cytokine production. PD-L1 is abundantly expressed on many murine and human cancers and can be upregulated upon IFN-gamma stimulation, suggesting its role in tumor immune evasion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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