Thermo Fisher Scientific DAB2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Immunohistochemistry (PFA fixed) (IHC (PFA))

-

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Published species

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human DAB2. Recombinant protein control fragment (Product #RP-102273). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:DAB2,uniProtId:P98082-1,ncbiNodeId:9606,antigenRange:278-397,antigenLength:770,antigenImageFileName:PA5-56005_DAB2_P98082-1_Rabbit.svg,antigenImageFileNamePDP:PA5-56005_DAB2_P98082-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2640364

Product Specific Information

Immunogen sequence: NAFSANLNFF PTPNPDPFRD DPFTQPDQST PSSFDSLKSP DQKKENSSSS STPLSNGPLN GDVDYFGQQF DQISNRTGKQ EAQAGPWPFS SSQTQPAVRT QNGVSEREQN GFSVKSSPNP

Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 82%.

Target Information

DAB2 mRNA is expressed in normal ovarian epithelial cells but is down-regulated or absent from ovarian carcinoma cell lines. The 770-amino acid predicted protein has an overall 83% identity with the mouse p96 protein, a putative mitogen-responsive phosphoprotein; homology is strongest in the amino-terminal end of the protein in a region corresponding to the phosphotyrosine interaction domain. The down-regulation of DAB2 may play an important role in ovarian carcinogenesis. This gene was initially named DOC2 (for Differentially expressed in Ovarian Cancer) and is distinct from the DOC2A and DOC2B genes (for double C2-like domains, alpha and beta).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.