Thermo Fisher Scientific TAF4B Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human TAF4B. Recombinant protein control fragment (Product #RP-89354). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TAF4B,uniProtId:Q92750-1,ncbiNodeId:9606,antigenRange:317-463,antigenLength:862,antigenImageFileName:PA5-56014_TAF4B_Q92750-1_Rabbit.svg,antigenImageFileNamePDP:PA5-56014_TAF4B_Q92750-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2648192

Product Specific Information

Immunogen sequence: PHLVPFLKKS VVALRQLLPN SQSFIQQCVQ QTSSDMVIAT CTTTVTTSPV VTTTVSSSQS EKSIIVSGAT APRTVSVQTL NPLAGPVGAK AGVVTLHSVG PTAATGGTTA GTGLLQTSKP LVTSVANTVT TVSLQPEKPV VSGTAVT

Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 70%.

Target Information

TAF II p105, also called TAF4B, is a celltype specific transcriptional co-activator that is a component of the TFIID complex. Expressed primarily in B cells and ovarian granulosa cells, TAF II p105 can interact with OCBA/POU2AF1 to activate B cell-specific octamerdependent transcription. Additionally, TAF II p105 plays an important role in co-activating the transcription factor NFkB and is essential for activation of anti-apoptotic genes such as TNFAIP3. TAF II p135, also known as TAF4, TAF2C, TAF2C1, TAF4A or TAFII130, is a 1,085 amino acid subunit of TFIID that accelerates transcriptional activation triggered by thyroid hormone (TR) or retinoic acid (RA). Localized to the nucleus, TAF II p135 contains one TAFH domain and is thought to bind to proteins that contain glutamine-rich domains, such as the transcription factor CREB.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.