Thermo Fisher Scientific TAF4B Polyclonal Antibody
TAF4B 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. IHC(P) 및 ICC/IF에 사용 가능하며, 항원 친화 크로마토그래피로 정제됨. Human 시료에 반응하며 4°C 또는 -20°C에서 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TAF4B. Recombinant protein control fragment (Product #RP-89354). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2648192 |
Product Specific Information
Immunogen sequence:
PHLVPFLKKS VVALRQLLPN SQSFIQQCVQ QTSSDMVIAT CTTTVTTSPV VTTTVSSSQS EKSIIVSGAT APRTVSVQTL NPLAGPVGAK AGVVTLHSVG PTAATGGTTA GTGLLQTSKP LVTSVANTVT TVSLQPEKPV VSGTAVT
Sequence identity:
- Mouse: 74%
- Rat: 70%
Target Information
TAF II p105, also called TAF4B, is a cell-type specific transcriptional co-activator that is a component of the TFIID complex. It is primarily expressed in B cells and ovarian granulosa cells, and interacts with OCBA/POU2AF1 to activate B cell-specific octamer-dependent transcription.
TAF II p105 also co-activates NFκB, essential for activation of anti-apoptotic genes such as TNFAIP3.
TAF II p135 (also known as TAF4, TAF2C, TAF2C1, TAF4A, or TAFII130) is a 1,085 amino acid subunit of TFIID that accelerates transcriptional activation triggered by thyroid hormone (TR) or retinoic acid (RA). Localized to the nucleus, it contains one TAFH domain and binds to proteins with glutamine-rich domains such as CREB.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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