Thermo Fisher Scientific Vimentin (Mesenchymal Cell Marker) Monoclonal Antibody (rVIM/6575)
중간엽 세포 마커인 Vimentin 단백질을 검출하는 Thermo Fisher Scientific의 단클론 항체로, 다양한 종에서 반응하며 Mouse에는 반응하지 않음. Western blot과 면역조직화학에 적합하며, 단백질 A/G로 정제된 액상 형태로 제공. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Dog, Chicken, Horse, Cat, Human, Pig, Rat |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | rVIM/6575 |
| Immunogen | Recombinant full-length human Vimentin protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Product Specific Information
Does not react with Mouse.
Target Information
Vimentin is a developmentally regulated intermediate filament protein (IFP) found in cells of mesenchymal origin. It is involved in the intracellular transport of proteins between the nucleus and plasma membrane. Vimentin, along with desmin, is expressed during early cellular development and later replaced by tissue-specific IFPs. It plays a role in steroid synthesis by facilitating cholesterol transport to mitochondria through cytoskeletal rearrangement induced by phosphorylation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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