Thermo Fisher Scientific CRALBP Polyclonal Antibody
CRALBP 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ELISA, IP에 사용 가능. Human, Mouse, Rat 반응성. 합성 펩타이드(aa 260-317)로 면역화. 고순도 친화 크로마토그래피 정제, -20°C 보관.
- 카탈로그번호
- RLBP1-101AP
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CRALBP Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 260–317 on human Retinaldehyde-binding protein 1 (CRALBP / RLBP1). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20 °C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cellular retinaldehyde-binding protein (CRALBP) plays a crucial role in the regeneration of 11-cis-retinal used in rod visual pigments such as opsin and rhodopsin. After photoisomerization in the rod outer segment, 11-cis-retinal is converted to all-trans-retinal and then to all-trans-retinol. This compound diffuses into the retinal pigment epithelium (RPE), where it is reconverted to 11-cis-retinol and oxidized into 11-cis-retinal, both processes involving CRALBP. Mutations in CRALBP are associated with visual disorders such as Bothnia dystrophy, retinitis punctata albescens, retinitis pigmentosa, and Newfoundland rod-cone dystrophy. CRALBP is a known marker for RPE and Müller glial cells of the retina.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.