Thermo Fisher Scientific CD79A Monoclonal Antibody (OTI3D3), TrueMAB
인간 CD79A 단백질을 인식하는 마우스 단클론 항체로, Western blot, IHC, 유세포분석에 사용 가능. 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도. B세포 관련 연구 및 면역표지에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:2,000 | - |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:150 | - |
| Flow Cytometry (Flow) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3D3 |
| Immunogen | Full length human recombinant protein of human CD79A produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
CD79a is a disulfide-linked heterodimer that includes the B29 (CD79b) polypeptide. It functions as part of the B lymphocyte antigen receptor complex, associating with Ig-alpha and Ig-beta, which are essential for B-cell receptor expression and signaling.
CD79a expression begins at the pre-B cell stage and continues until the plasma cell stage, where it is found intracellularly. It is present in most precursor B-cell acute leukemias, B-cell lines, B-cell lymphomas, and some myelomas, but absent in myeloid or T-cell lines.
Diseases associated with CD79a include Agammaglobulinemia 3 and Agammaglobulinemia, Non-Bruton type.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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