Thermo Fisher Scientific HNRNPM Monoclonal Antibody (OTI1F6), TrueMAB

Applications and Tested Dilution

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

Heterogeneous nuclear ribonucleoproteins (hnRNPs) are RNA-binding proteins that associate with nascent RNA polymerase II transcripts and are involved in transcript-specific packaging and alternative splicing of pre-mRNAs.
The M1–M4 hnRNP proteins form a cluster of four pre-mRNA binding proteins that bind strongly to poly(G) and poly(U) RNA homopolymers. These proteins share homology with RNA-binding proteins from Saccharomyces cerevisiae and contain a methionine/arginine-rich hexapeptide repeat (MR motif) similar to that found in the 64 kDa subunit of cleavage stimulation factor, which is involved in pre-mRNA 3′-end processing.
Proteins immunologically related to M exist in a wide range of eukaryotes from humans to yeast.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.