Thermo Fisher Scientific CIITA Polyclonal Antibody
상품 옵션 정보 | |||||||||
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카탈로그 번호 | CAS 번호 | 설명 | 상태 | 재고 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
PA585540 | - | Thermo Fisher Scientific PA585540 CIITA Polyclonal Antibody 100 ul pk | 재고문의 | pk | 673,000원 | - | 740,300원 |
다른 상품 둘러보기
Applications
Tested Dilution
Publications
Western Blot (WB)
1:500-1:3,000
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit / IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human CIITA.
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
1.31 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2792680
Product Specific Information
Keep as concentrated solution.
Positive Control: Raji, Raji NE.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
CIITA contains an acidic transcriptional activation domain, four LRRs (leucine-rich repeats) and a GTP binding domain. It is located in the nucleus and acts as a positive regulator of class II major histocompatibility complex gene transcription, and is referred to as the master control factor
for the expression of these genes. CIITA also binds GTP and uses GTP binding to facilitate its own transport into the nucleus. Once in the nucleus it does not bind DNA but rather uses an intrinsic acetyltransferase (AT) activity to act in a coactivator-like fashion. Mutations in this gene have been associated with bare lymphocyte syndrome type II (also known as hereditary MHC class II deficiency or HLA class II-deficient combined immunodeficiency), increased susceptibility to rheumatoid arthritis, multiple sclerosis, and possibly myocardial infarction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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