Thermo Fisher Scientific Phospho-Shp2 (Tyr580) Recombinant Rabbit Monoclonal Antibody (Shp2Y580-4A2), APC
APC 형광 표지된 Recombinant Rabbit Monoclonal 항체로 Tyr580 위치의 인산화 Shp2 단백질을 특이적으로 인식합니다. 인간 및 생쥐 시료에 반응하며 Flow Cytometry에 적합합니다. 고순도 Protein A/G 정제, PBS+BSA buffer로 안정적 보관 가능.
- 판매단위
- pk
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Thermo Fisher Scientific Phospho-Shp2 (Tyr580) Recombinant Rabbit Monoclonal Antibody (Shp2Y580-4A2), APC
Applications
- Flow Cytometry (Flow)
Tested Dilution: 5 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | Shp2Y580-4A2 |
| Immunogen | Synthetic phospho-peptide corresponding to residues surrounding Tyr580 of human phospho Shp2 |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.20% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2896915 |
Additional Formats
- Unconjugated: MA5-36977
- FITC: MA5-36979
- PE: MA5-36978
- Custom conjugation available upon request
Target Information
The protein encoded by this gene belongs to the protein tyrosine phosphatase (PTP) family. PTPs act as signaling molecules that regulate various cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation.
This PTP contains two tandem Src homology-2 domains that mediate interactions with phospho-tyrosine substrates. It is widely expressed and plays a regulatory role in cell signaling related to mitogenic activation, metabolic control, transcription regulation, and cell migration.
Mutations in this gene are associated with Noonan syndrome and acute myeloid leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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