Thermo Fisher Scientific FGFR1 Polyclonal Antibody
FGFR1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Human 및 Mouse 시료에 반응합니다. Western blot, IHC, Flow Cytometry 등 다양한 응용에 적합하며, 고순도 및 안정적인 액상 형태로 제공됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Immunohistochemistry (IHC) | - | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:50 | - |
| Flow Cytometry (Flow) | 1:10–1:50 | - |
| in situ PLA (PLA) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | His fusion protein from human N-terminal FGFR1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Ammonium sulfate precipitation, size-exclusion, dialysis |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2543479 |
Target Information
FGFR1 (also known as FLT2) is a member of the Fibroblast Growth Factor Receptor family, consisting of four membrane-spanning tyrosine kinases (FGFR1–4) that serve as high-affinity receptors for 17 growth factors (FGF1–17).
The FGF receptor family plays a key role in biological processes such as mesoderm induction, cell growth and migration, organ formation, and bone development.
FGFR1 undergoes alternative splicing, generating multiple variants expressed differently during embryonic and adult stages.
Defects in FGFR1 are associated with several disorders including Pfeiffer syndrome, idiopathic hypogonadotropic hypogonadism, Kallmann syndrome type 2, osteoglophonic dysplasia, and others.
Chromosomal aberrations involving FGFR1 can lead to stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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