Thermo Fisher Scientific HCK Polyclonal Antibody
HCK 단백질에 특이적인 Rabbit Polyclonal Antibody로 Western blot 및 IHC(Paraffin)에서 검증됨. 인간 반응성, 단백질 A 및 항원 친화 크로마토그래피로 정제. 0.5 mg/mL 농도의 액상 형태로 제공되며, 단기 4°C 보관 및 장기 -20°C 보관 권장.
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- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide between amino acids 131–156 from the N-terminal region of human HCK |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2543489 |
Product Specific Information
This antibody is predicted to react with mouse, non-human primate, and rat based on sequence homology.
Target Information
Hematopoietic cell kinase (HCK) is a SRC-related kinase expressed in lymphoid and hematopoietic cells and may play a role in certain forms of leukemia. HCK (Alias: DKFZp686D0638) is a protein-tyrosine kinase predominantly expressed in hemopoietic cell types. The encoded protein may couple the Fc receptor to activation of the respiratory burst and play roles in neutrophil migration and degranulation. Alternate translation initiation, including a non-AUG (CUG) codon, results in two isoforms with different subcellular localizations.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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