Thermo Fisher Scientific Carbonic Anhydrase III Polyclonal Antibody
Rabbit polyclonal antibody against Carbonic Anhydrase III for WB and IHC(P). Recognizes human and mouse CA3. Supplied as liquid, unconjugated, purified by size-exclusion and dialysis. Suitable for research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:50 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide between amino acids 146–177 from the central region of human CA3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Size-exclusion, Dialysis, Ammonium sulfate precipitation |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2543477 |
Target Information
Carbonic anhydrase III (CAIII) is a member of a multigene family encoding carbonic anhydrase isozymes. These metalloenzymes catalyze the reversible hydration of carbon dioxide and are differentially expressed in various cell types. The CA3 gene is expressed at high levels in skeletal muscle and at lower levels in cardiac and smooth muscle. Elevated CA3 levels have been observed in some carriers of Duchenne muscular dystrophy. The gene spans approximately 10.3 kb and contains seven exons and six introns.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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