Thermo Fisher Scientific ERCC1 Monoclonal Antibody (OTI3F6), TrueMAB
ERCC1 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot에 1:2,000 희석 비율로 적합합니다. 인간 시료에 반응하며, TrueMAB 기술로 제작되었습니다. Lyophilized 형태로 제공되며 PBS buffer에 trehalose 포함, -20°C 보관 권장.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3F6 |
| Immunogen | Full length human recombinant protein of human ERCC1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
ERCC1 is a non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5′ incision during DNA repair. It works with SLX4 in the repair of interstrand cross-links (ICL) and participates in processing anaphase bridge-generating DNA structures that can lead to cytokinesis failure. ERCC1 is also essential for homology-directed repair (HDR) of DNA double-strand breaks in conjunction with SLX4. (Uniprot)
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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