Thermo Fisher Scientific RAB27A Monoclonal Antibody (4D3F11)

Applications

Tested Dilution

Publications

Western Blot (WB)

0.5-2 µg/mL

-

Flow Cytometry (Flow)

5-20 µg/mL

-

Immunoprecipitation (IP)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

4D3F11

Immunogen

Recombinant full length protein corresponding to Human RAB27A aa 1-221. Expressed in E. coli. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RAB27A,uniProtId:P51159-1,ncbiNodeId:9606,antigenRange:1-221,antigenLength:221,antigenImageFileName:MA1-172_RAB27A_P51159-1_House_mouse.svg,antigenImageFileNamePDP:MA1-172_RAB27A_P51159-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4, with 1mg/mL BSA, 30% glycerol

Contains

0.05% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2608617

Target Information

The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.