Thermo Fisher Scientific ASPP2 Polyclonal Antibody
Rabbit polyclonal antibody against ASPP2 (53BP2), validated for WB and IP applications. Targets human apoptosis-stimulating protein of p53 region (residues 425–475). Supplied as liquid, unconjugated form with 0.20 mg/mL concentration. For research use ...
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 425 and 475 of human Apoptosis-Stimulating Protein of p53, 2 (53BP2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions.
Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo.
Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis.
Impedes cell cycle progression at G2/M.
Its apoptosis-stimulating activity is inhibited by its interaction with DDX42.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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