Thermo Fisher Scientific GM-CSF Monoclonal Antibody (KT35)
Thermo Fisher Scientific의 GM-CSF Monoclonal Antibody (KT35)는 인간 GM-CSF 단백질을 표적으로 하는 Rat IgG2a 형 단클론 항체입니다. Western blot과 ELISA에 적합하며, Protein G로 정제된 액상 형태로 제공됩니다. 연구용으로만 사용되며, 장기 보관 시 -20°C에서 보관하십시오.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| ELISA | 1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rat / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | KT35 |
| Immunogen | Recombinant Human CSF2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3090647 |
Product Specific Information
This antibody was used in both Indirect and Sandwich ELISA assays.
Target Information
The GM-CSF gene encodes a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes. The active form of the protein exists as a homodimer in the extracellular space. This gene is located in a cluster of related genes at chromosome region 5q31, associated with interstitial deletions in 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include interleukins 4, 5, and 13.
GM-CSF is involved in promoting tissue inflammation, and elevated levels have been observed in SARS-CoV-2 infected patients with acute respiratory distress syndrome. Mice lacking this gene or its receptor develop pulmonary alveolar proteinosis.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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