
Thermo Fisher Scientific SPA17 Monoclonal Antibody (OTI3E9), TrueMAB
인간 SPA17 단백질을 인식하는 마우스 단일클론 항체로 Western blot에 적합합니다. 동결건조 형태로 제공되며, 재구성 시 약 1 mg/mL 농도로 사용 가능합니다. 세포 간 접착 및 면역세포 이동 연구에 유용합니다.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3E9 |
| Immunogen | Full length human recombinant protein of human SPA17 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
This gene encodes a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa), while the C-terminus contains an IQ calmodulin-binding motif.
The central region includes carbohydrate-binding motifs and is involved in cell-cell adhesion. Initially identified for its role in sperm binding to the zona pellucida, SPA17 also participates in immune cell migration and metastasis. A retrotransposed pseudogene is located on chromosome 10q22.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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