
Thermo Fisher Scientific SPA17 Monoclonal Antibody (OTI1G1), TrueMAB
인간 SPA17 단백질을 인식하는 Mouse Monoclonal Antibody. Western blot에 최적화되어 있으며, 비결합형 형태로 제공. 친화 크로마토그래피로 정제되어 높은 순도 보장. 동결건조 형태로 보관이 용이하며, 연구용으로 적합.
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Applications
- Western Blot (WB): 1:2,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1G1 |
| Immunogen | Full length human recombinant protein of human SPA17 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, it is recommended to perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
This gene encodes a protein located at the cell surface. The N-terminus shows similarity to the cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa), while the C-terminus contains an IQ calmodulin-binding motif.
The central region includes carbohydrate-binding motifs, suggesting a role in cell-cell adhesion. Initially identified for sperm binding to the zona pellucida, SPA17 is now known to participate in immune cell migration and metastasis.
A retrotransposed pseudogene is located on chromosome 10q22.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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