Thermo Fisher Scientific CD2 Monoclonal Antibody (UMAB86), UltraMAB
인간 CD2 단백질을 인식하는 UMAB86 클론의 마우스 단일클론 항체로, Western blot, IHC, ICC/IF, Flow cytometry 등 다양한 분석에 사용 가능. 무보존제, 동결건조 형태로 제공되며 재구성 후 1 mg/mL 농도로 사용. 연구용으로만 사용 가능.
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Thermo Fisher Scientific CD2 Monoclonal Antibody (UMAB86), UltraMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | Assay-dependent |
| ChIP Assay (ChIP) | Assay-dependent |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UMAB86 |
| Immunogen | Full-length human recombinant CD2 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
CD2 (LFA-2) is a monomeric surface antigen (MW 45–58 kDa) expressed on human T-lymphocytes and some NK cells, but not on B lymphocytes.
It mediates adhesion between T cells and antigen-presenting cells via interaction with CD58, stabilizing cell-cell contact.
CD2 expression increases upon T-cell activation, enhancing immune response.
Deficiency in CD2 can reduce intestinal inflammation and affect infection control.
Associated diseases include penile squamous cell carcinoma and immune deficiency due to thymus absence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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