Thermo Fisher Scientific TFEB Recombinant Rabbit Monoclonal Antibody (8M8Y8)
TFEB 단백질을 인식하는 재조합 토끼 단일클론 항체로, Western blot과 ELISA에 적합합니다. 높은 특이성과 재현성을 제공하며, HEK293 세포에서 발현된 IgG 형 항체입니다. 인간 TFEB(아미노산 50–173) 서열 기반 면역원으로 제작되었습니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:9,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 8M8Y8 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 50–173 of human TFEB (NP_009093.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.81 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_3093095 |
Product Specific Information
Immunogen sequence:
TPAINTPVHF QSPPPVPGEV LKVQSYLENP TSYHLQQSQH QKVREYLSET YGNKFAAHIS PAQGSPKPPP AASPGVRAGH VLSSSAGNSA PNSPMAMLHI GSNPERELDD VIDNIMRLDD VLGY
Target Information
The Transcription factor EB (TFEB) is a member of the basic helix-loop-helix leucine zipper superfamily of transcription factors that is translocated in a subset of renal tumors.
Recent studies have shown that lysosomal biogenesis is regulated by TFEB, which is in turn regulated by the mammalian target of rapamycin (mTOR) complex 1.
Other evidence suggests that TFEB coordinates the major steps of the autophagic pathway by driving the expression of autophagy and lysosomal genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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