Thermo Fisher Scientific Phospho-Smad3 (Ser423) Polyclonal Antibody
Phospho-Smad3 (Ser423) 폴리클로날 항체로 인간, 마우스, 랫트 반응성을 가지며 TGF-β 신호전달 연구에 활용 가능. Western blot, IHC, Flow cytometry, ELISA 등 다양한 응용에 적합. 고순도 Protein A 정제, 안정적 액상 형태로 제공.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300 |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Flow Cytometry (Flow) | 1:20–1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic phosphopeptide derived from human Smad3 around the phosphorylation site of Ser423 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
SMAD3 belongs to the SMAD family of proteins, which are homologous to the Drosophila gene mothers against decapentaplegic (Mad) and the C. elegans gene Sma. SMAD proteins act as signal transducers and transcriptional modulators mediating multiple signaling pathways. SMAD3 functions as a transcriptional modulator activated by transforming growth factor-beta (TGF-β) and is implicated in the regulation of carcinogenesis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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