Thermo Fisher Scientific CD4 Monoclonal Antibody (CT7), FITC

Applications

• Flow Cytometry (Flow)
  Tested Dilution: Neat-1:10

Product Specifications

Additional Formats

• Unconjugated
• PE
• Request custom conjugation

Product Specific Information

For FACS analysis, use 10 µL of the suggested working dilution to label 1×10⁶ cells in 100 µL.
Mouse anti-Guinea Pig CD4 antibody, clone CT7, recognizes the CD4 antigen present on T Helper/Inducer lymphocytes.

Target Information

The CD4 antigen is involved in the recognition of MHC class II molecules and acts as a co-receptor for HIV.
CD4 is primarily expressed in T helper cells, but also in monocytes, macrophages, and dendritic cells.
At the tissue level, CD4 expression may be detected in thymus, lymph nodes, tonsils, spleen, and also in brain, gut, and other non-lymphoid tissues.
CD4 functions to initiate or augment the early phase of T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase Lck.
It may also mediate neuronal damage in infectious and immune-mediated diseases of the CNS.
Multiple alternatively spliced transcripts have been identified (RefSeq, July 2017).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지