Thermo Fisher Scientific HIV1 gp120 Synthetic Peptide
HIV-1 gp120 중심부의 15개 아미노산으로 구성된 합성 펩타이드. 폴리클로날 항체 PA5-20584의 블로킹 펩타이드로 사용 가능. 액상 형태로 제공되며, 1 mg/mL 농도. PBS(pH 7.2, 0.1% BSA) 버퍼에 보관, -20°C에서 안정적 저장.
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Thermo Fisher Scientific HIV1 gp120 Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 15 amino acids near the center of HIV-1 gp120.
PEP-0704 can be used as a blocking peptide with polyclonal antibody PA5-20584.
Target Information
Human immunodeficiency virus type 1 (HIV-1) entry into target cells is directed by the envelope (Env) glycoproteins, which are present on the surface of HIV-1 virion or infected cells in the form of trimers consisting of gp120/gp41 complexes.
The surface subunit, gp120, initiates the entry process by interacting sequentially with the CD4 receptor and a co-receptor CCR5 or CXCR4, thereby inducing a conformational change that allows the transmembrane (TM) gp41 subunit to mediate fusion between viral and target cell membranes.
Cleavage of Env into its gp120 and gp41 components is necessary for activation of its fusogenic activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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