Thermo Fisher Scientific MSF Polyclonal Antibody
Western blot, IHC, ELISA, IP 등 다양한 응용에 적합한 Rabbit Polyclonal Antibody. Human, Mouse, Rat에 반응하며, 합성 펩타이드(aa 1-60, SEPT9)로부터 제작. 친화 크로마토그래피로 정제된 액상 항체로, -20°C 보관. 연구용 전용 시약.
- 카탈로그번호
- SEPT-901AP
- 판매단위
- pk
카탈로그
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:100 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 1–60 on SEPT9 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The maf oncogene was identified by structural analysis of the AS42 avian transforming retrovirus genome. The Maf family is divided into two subclasses: large Mafs (vMaf, cMaf, MafB, Nrl) and small Mafs (MafF, MafK, MafG). Both subclasses contain leucine zipper motifs enabling homo- and heterodimerization with various bZip transcription factors. Large Mafs possess an acidic transactivation domain absent in small Maf proteins.
Small Mafs can act as positive transcriptional regulators by targeting active dimerization partners to specific DNA elements or as negative regulators by recruiting repressors or forming inactive homodimers. Human MafF, isolated from a human myometrium cDNA library, encodes a 164-amino-acid protein with an extended leucine zipper and no N-terminal transactivation domain. These small Maf proteins are implicated in development, differentiation, hematopoiesis, and stress response, each regulating stress via distinct mechanisms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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