Thermo Fisher Scientific MSF Polyclonal Antibody, FITC
FITC로 표지된 Thermo Fisher Scientific의 MSF 폴리클로날 항체로, Western blot, ELISA, IP에 사용 가능. 인간, 마우스, 랫트 반응성. 합성 펩타이드(1-60 aa) 면역원 사용. 액상 형태로 -20°C, 암소 보관. 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 1–60 on SEPT9 protein |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The maf oncogene was identified by structural analysis of the AS42 avian transforming retrovirus genome. The Maf family is divided into two subclasses, large Mafs (vMaf, cMaf, MafB, and Nrl) and small Mafs (MafF, MafK, and MafG). Both subclasses contain leucine zipper motifs that allow homo- and heterodimerization with other bZip transcription factors. Large Mafs contain an acidic transactivation domain absent in small Maf proteins. Although small Mafs lack inherent transactivation activity, they can act as positive regulators by targeting active dimerization partners to specific DNA regulatory elements. Conversely, they can also act as negative regulators by recruiting repressors or forming inactive homodimers. Human MafF was isolated from a human myometrium cDNA library and encodes a 164-amino acid protein with an extended leucine zipper but no N-terminal transactivation domain. Small Maf proteins are implicated in development, differentiation, hematopoiesis, and stress response, each via distinct mechanisms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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