Thermo Fisher Scientific MSF Polyclonal Antibody, Biotin
Biotin으로 표지된 Thermo Fisher Scientific의 MSF Polyclonal Antibody는 Human, Mouse, Rat에 반응하며 Western blot, ELISA, Immunoprecipitation에 적합합니다. SEPT9 단백질의 1-60 아미노산 영역을 면역원으로 사용한 Rabbit IgG 항체로, 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide taken within amino acid region 1–60 on SEPT9 protein |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The maf oncogene was identified by structural analysis of the AS42 avian transforming retrovirus genome. The Maf family is divided into two subclasses: large Mafs (vMaf, cMaf, MafB, and Nrl) and small Mafs (MafF, MafK, and MafG). Both subclasses contain leucine zipper motifs, allowing homodimerization and heterodimerization with other bZip transcription factors.
Large Mafs possess an acidic transactivation domain, absent in small Maf proteins. Although small Mafs lack inherent transactivation activity, they can act as positive transcription regulators by recruiting active dimerization partners to specific DNA elements. Conversely, they may act as negative regulators by forming homodimers or recruiting repressors.
Human MafF was isolated from a human myometrium cDNA library and encodes a 164-amino-acid protein. Like other small Maf proteins, it contains an extended leucine zipper structure and lacks an N-terminal transactivation domain. Small Maf proteins are involved in development, differentiation, hematopoiesis, and stress response, regulating these processes via different mechanisms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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