Thermo Fisher Scientific SETD8 Polyclonal Antibody
Human SETD8/PR-Set7 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 ELISA에 사용 가능. 보존제가 없는 액상 형태이며, Protein A 및 항원 친화 크로마토그래피로 정제됨. 세포 증식 및 염색질 구조 연구용으로 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1:25,000–1:50,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human SETD8/PR-Set7 Protein (Lys195–His352) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A, Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | No preservative |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2788044 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human SETD8/PR-Set7.
Target Information
SETD8 is a histone methyltransferase that specifically monomethylates Lys-20 of histone H4. H4 Lys-20 monomethylation is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression.
The protein mainly functions in euchromatin regions, playing a central role in silencing euchromatic genes. It is required for cell proliferation, contributing to the maintenance of proper higher-order DNA structure during mitosis.
SETD8 is also involved in chromosome condensation and proper cytokinesis. Nucleosomes are preferred as substrate compared to free histones.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(PA5-80762_SETD8_Q9NQR1-1_Rabbit.svg 및 PA5-80762_SETD8_Q9NQR1-1_Rabbit_PDP.jpeg 이미지 포함)
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